After spending the better part of an evening figuring this out, I can say the Chunk is one of those enemies in Resident Evil Requiem that feels impossible until you understand how tightly the encounter is scripted. On my first run as Grace in Rhodes Hill Care Center, I did what most players do: I sprinted past him, burned way too much pistol ammo trying to stagger him, and basically treated him like an unkillable pursuer. That was a mistake.
Once I learned how Hemolytic Injectors work and how safe rooms in the East Wing limit Chunk’s movement, the fight went from “panic chase” to a controlled stealth execution that took about 15 minutes start to finish. Doing it properly lets you:
If you’re at the point where Chunk has just spawned and you’re wondering whether to run or stand your ground, this guide walks you through the safe, resource-efficient way to kill him with Grace, using Hemolytic Injectors and, optionally, a Requiem bullet.
You encounter the Chunk while playing as Grace in the Rhodes Hill Care Center, specifically in the East Wing. The trigger is tied to your story progress:
Your immediate goal is to survive that first surprise. You do not need to kill him during the initial chase. Instead:
Don’t make my mistake of deciding to kill Chunk without enough resources. I had to backtrack, farm materials, then reset his patrol again. Here’s what you should have ready before you seriously go for the kill.
The safest and most consistent method is to use Hemolytic Injectors on his back. In Standard difficulty, you should plan for:
Injectors are craftable. From my runs and testing:
I strongly recommend you sit in a safe room, open the crafting menu, and make sure you can build at least two injectors before you start poking the giant meat wall.
Grace can use Requiem bullets with Leon’s gifted weapon. These rounds are powerful but extremely limited. You can craft more with rare materials like Rare Metal, usually found via lockpicks and high-value containers, but you won’t be swimming in them.
In my Standard playthrough, I confirmed that:
If you’re low on injector materials but sitting on a Requiem round you haven’t used, keep that 2+1 option in mind. Just know that a missed headshot hurts a lot more than a flubbed injector attempt.
Once you’ve escaped the initial chase, Chunk settles into a patrol around the East Wing’s ground floor. From watching him over several attempts, his usual route is:
This is critical: some rooms act as safe zones he will not enter. In my experience:
Most of the fight boils down to dancing between these two rooms and the hallway between them. You wait until his back is turned, slip out, get behind him, and stab him with an injector.
This is the method I recommend for most players on Standard. It’s ammo-friendly and very forgiving as long as you respect his patrol.
Start in the Waiting Room with your injectors crafted and ready.
Your goal is to wait until he walks past the Waiting Room door with his back turned, heading toward the Examination Room side of the corridor.
When his back is safely turned and he’s a few steps away:
He’ll react violently, but you have a small window right after the stab. As soon as the animation ends:
After he calms down, his patrol resumes. The pattern repeats:
This second hit usually makes him more visibly unstable-his movements get jerkier, and he leaks more blood, but he’s still deadly if you get cornered. Again, immediately retreat to a safe room once the stab completes.
After the second injector, you’re in the danger-but-almost-done phase. This is where impatience kills most runs.
Once the third injector lands, Chunk will start to crumple and spew blood dramatically. That’s your sign the hemolysis is finally finishing him off. Step back, give him space, and let the death animation play out; you don’t need to do anything else.
When he fully explodes and collapses, the area quiets down. Approach the bloody remains and you’ll be able to pick up the Eye Spy Charm from the pool of gore.
On one of my attempts, I was short on Infected Blood but had a spare Requiem bullet I hadn’t used. I experimented with a hybrid approach, which worked on Standard:
That final high-damage shot pushed him into the same bloody, collapsing death animation as a third injector. The big caveat is that Requiem ammo is much harder to replace than injector materials, so:
L2/LT aim and wait until he’s walking straight away from you.I haven’t personally tested this on higher difficulties, so treat it as a Standard-mode backup tactic rather than the main recommended strategy.
Most of my failed attempts came from playing too aggressively. Here are the big pitfalls you can avoid.
If you mess up an injector attempt and he spots you, just sprint back into the nearest safe room and reset. Don’t try to salvage the run with desperation shots in the open hallway; that’s how I lost most of my healing items in one failed attempt.
Once Chunk is dead, you immediately get two big payoffs:
There’s also a practical, exploration-focused benefit that I didn’t appreciate until my second run: if you leave Chunk alive, he continues to patrol and can even devour NPCs or zombies that cross his path, sometimes relocating to awkward spots like the Blood Lab hallway. That makes backtracking and 100% exploration much more stressful.
By killing him while you’re still focused on the East Wing, you turn that entire section into a much safer zone for later item cleanup and puzzle-solving.
If you want a quick mental checklist before you dive back in:
Once you’ve done it once, the whole encounter feels much less like a horror set piece and more like a puzzle: use the safe rooms, respect the patrol, and let the injectors do the heavy lifting. If I could turn this from a chaotic ammo dump into a clean three-step execution, you can absolutely do the same.
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